Healthcare

1. Electronic Health Records (EHR) & Hospital Information Systems

Major EHR Platforms

• OpenMRS: Global open-source EHR platform for resource-constrained environments

  • Modular architecture, used in 60+ countries

  • Strong global health focus, HIV/TB program management

• GNU Health: Hospital management and EHR system

  • Includes modules for genetics, laboratory, surgery

  • Used in public health systems worldwide

• FreeMED: Practice management and EHR system

• OpenEMR: Most widely adopted open-source EHR

  • ONC-certified, Meaningful Use compliant

  • Used by thousands of practices globally

Hospital Management Systems

• Bahmni: Built on OpenMRS for hospital information systems

  • Integrated with OpenELIS (lab) and OpenERP (financials)

• HOSxP: Popular in Thailand and Southeast Asia

• DHIS2: Health management information system (more than just EHR)

  • Used in 70+ countries for aggregate health data

2. Medical Imaging & PACS

Picture Archiving and Communication Systems (PACS)

• Orthanc: Lightweight, RESTful PACS server

  • DICOM standard compliant, plugin architecture

• DCM4CHEE: Enterprise imaging platform

  • Full-featured PACS, RIS, and image management

• OpenREM: Radiation dose monitoring system

• XNAT: Imaging informatics platform for research

DICOM Viewers & Processing

• OHIF Viewer: Web-based zero-footprint DICOM viewer

  • React-based, extensible architecture

• 3D Slicer: Medical visualization and analysis

  • Advanced image processing, surgical planning

• Horos: MacOS DICOM viewer (based on OsiriX)

• Weasis: Java-based DICOM viewer with web capabilities

3. Public Health & Surveillance

Health Information Systems

• DHIS2: District Health Information Software

  • The world’s largest health management information system

  • Used for aggregate data, analytics, and visualization

• OpenHDS: Open Health Data Services for longitudinal cohort studies

• Go.Data: WHO’s outbreak investigation tool (field data collection)

• SORMAS: Surveillance, Outbreak Response Management & Analysis System

COVID-19 Response Tools

• CommCare: Mobile data collection platform (open core)

• OpenSRP: Smart Register Platform for frontline workers

• COVID-19 Registry: Open source patient management systems

4. Laboratory Information Systems (LIS)

• OpenELIS: Global lab information system

  • Supports public health laboratories

• SENAITE: Modern LIMS built on Plone

  • Sample management, reporting, QC

• Bika LIMS: Web-based laboratory information management

• GNU Health LIMS: Laboratory module within GNU Health

5. Telemedicine & Remote Care

• HAPI FHIR: Healthcare API for interoperability

• OpenTelehealth: Platform for remote monitoring

• LibreHealth EHR: With telemedicine modules

• Simple telehealth solutions: Jitsi Meet integration for video consultations

• Bluetooth COVID-19 contact tracing apps: Many open source implementations

6. Genomics & Bioinformatics

Analysis Platforms

• Galaxy: Web-based platform for computational biology

  • Accessible bioinformatics for non-programmers

• GATK: Genome Analysis Toolkit (now open source)

  • Industry standard for variant discovery

• Bioconductor: R-based bioinformatics packages

Visualization & Management

• IGV: Integrative Genomics Viewer

• CROMWELL: Workflow management system

• DNAnexus (open core): Cloud-based genomics platform

7. Clinical Decision Support & AI

CDS Systems

• OpenCDS: Clinical decision support platform

  • Knowledge management and decision engine

• Inferno: ONC’s testing tool for FHIR standards

• Clinical Quality Language (CQL): Standard for expressing clinical knowledge

Medical AI/ML Frameworks

• MONAI: Medical Open Network for AI (based on PyTorch)

• NiftyNet: Deep learning platform for medical imaging

• 3D Slicer with AI extensions

• TensorFlow/PyTorch with medical imaging extensions

8. Interoperability & Standards

FHIR (Fast Healthcare Interoperability Resources)

• HAPI FHIR: Leading Java implementation

• FHIR Server for Azure: Microsoft’s open implementation

• Smile CDR: Commercial with open community edition

• Firely: .NET FHIR implementation

Other Standards Implementation

• OpenHIM: Health information mediator for interoperability layers

• Mirth Connect: Interface engine (open source version available)

• OpenID Connect & SMART on FHIR: For authentication/authorization

9. Mobile Health (mHealth)

• ODK (Open Data Kit): Mobile data collection

• CommCare: Community health worker platform

• OpenSRP: Mobile platform for frontline workers

• Collect.earth: For geographic data collection

• RD Client: RedCap mobile alternative

10. Pharmacy & Medication Management

• OpenPharmacy: Dispensary management

• HospitalRun (pharmacy module): Now part of Medplum ecosystem

• OpenEMR’s e-prescribing: Integration with SureScripts

• Pharmacogenomics tools: Open source implementations

11. Dental & Specialty Care

• Open Dental: Practice management software

• GNU Dental: Part of GNU Health

• Ophthalmic EHRs: Several open source options

• Behavioral health systems: Like OpenBeds for psychiatric care

12. Research & Clinical Trials

Clinical Research Platforms

• REDCap: Web-based electronic data capture (free for non-profits)

• OpenClinica: Clinical trial software

• LabKey Server: Biomedical research platform

• Caisis: Cancer data management system

Data Science & Analysis

• i2b2 (Informatics for Integrating Biology & the Bedside): Clinical data warehouse

• TransMART: Translational research platform

• OHDSI/OMOP: Observational health data sciences initiative tools

13. Government & Global Health Initiatives

National/Regional Systems

• India: National Digital Health Mission open source components

• Norway: FHIR-based national infrastructure

• Vietnam: OpenMRS-based national HIV system

• South Africa: DHIS2 for national health data

Global Collaborations

• WHO’s Digital Health Toolkit: Open source recommendations

• Mozilla’s Open Source COVID-19 Data Project

• UNICEF’s RapidPro: Open source communication platform

14. Development Frameworks & Tools

Healthcare-Specific Frameworks

• Medplum: Open source FHIR server and components

• FHIR.js: JavaScript FHIR library

• Fhirbase: PostgreSQL-based FHIR storage

• Clinical Fast Healthcare Interoperability Resources (C-FHIR)

General OSS in Healthcare IT

• Kubernetes/Docker: For healthcare application deployment

• PostgreSQL/PostGIS: With healthcare extensions

• Elastic Stack: For healthcare analytics and monitoring

• Keycloak: For identity and access management

15. Notable Projects & Case Studies

Impactful Implementations

1. OpenMRS in Kenya & Rwanda: National-scale HIV treatment programs

2. DHIS2 in Tanzania: National health management information system

3. Bahmni in Bangladesh: Hospital system for low-resource settings

4. GNU Health in Spain: Regional public health implementations

Innovative Projects

• Project Buendia: Field hospital EHR (used in Ebola response)

• HospitalRun: Modern web-based hospital system

• MedFlux: Open source medical device integration